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Methyl protodioscin

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Product Overview
Product Name Methyl protodioscin
CAS54522-52-0
FormulaC52H86O22
MW1063.23
Appearance 白色粉末
Melting point175-177 °C
PKa12+-.0.70 | Condition: Most Acidic Temp: 25 °C
Product details

WKQ-0000300

中文名稱:甲基原薯蕷皂苷

中文別名:甲基原薯蕷皂甙

英文名稱:Methyl protodioscin

英文別名:(3β,22α,25R)-26-(β-D-Glucopyranosyloxy)-22-methoxyfurost-5-en-3-yl O-6-deoxy-α-L-mannopyranosyl-(1→2)-O-[6-deoxy-α-L-mannopyranosyl-(1→4)]-β-D-glucopyranoside;22-Methoxylprotodioscin;22-O-Methylprotodioscin;3β,26-Dihydroxy-22α-methoxyfurost-5-ene 3-O-β-chacotrioside 26-O-β-D-glucopyranoside;Methylprotodioscin;NSC 698790;Smilax saponin B;

分子式:C52H86O22

分子量:1063.23

CAS號:54522-52-0

純度:HPLC≥98%

熔點:175-177 °C

密度:1.43±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr

酸系度數(shù):12+-.0.70 | Condition: Most Acidic Temp: 25 °C

儲存條件:-20℃,干燥、避光、密封

規(guī)格:5mg10mg20mg50mg100mg500mg1g2g等應客戶需求包裝

供應單位:四川省維克奇生物科技有限公司

供應電話:028-81700200/4008005713

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Related literature
Drug interaction study of natural steroids from herbs specifically toward human UDP-glucuronosyltransferase (UGT) 1A4 and their quantitative structure activity relationship (QSAR) analysis for prediction
Source:SCI:PHARMACOLOGICAL RESEARCH Author:Min Xu Notes:影響因子:4.816
Reference description

hecogenin (1), diosgenin (2), ruscogenin (3), gitogenin (4), tigogenin (5), solasodine (6), (24S,25S)-3β, 24-di-hydroxy-5α-spirostan (7), dracaenol C (8), 25(27)-dehydroruscogenin (9), (1β, 3β, 14α, 15α, 20R, 22S, 25R)-spirost-5-ene-tetrol (10), peimine (11), peiminine (12), peimisine (13), isoverticine (14), trillin (15), polyphyllin VI (16), polyphyllin VII (17), pallidifloside D (18), prosapogenin A (19), spongipregnoloside A (20), dioscin(21), solasonine (22), solamargine (23), gracillin (24), polyphyllin I(25), timosaponin BII (26), timosaponinA-III(27), ophiopogonin D (28), protobioside (29), (22S,25S)-26-O-β-d-glucopyranosyl-22,25-epoxyfurost-5-en-3β,26-diol-3-O-α-l-rha-mnopyranosyl(1 → 2)-β-d-gluc (30), pallidifloside E (31), parispseudoside (32), methylprotodioscin (33), protodioscin (34), pseudoprotodioscin (35), YS-IX (36), pallidifloside A (37), pallidifloside H (38), digoxin (39), bisdigoxigenin (40), 7β, 14α, 21-tri-hydroxy-diosgenin (41), 12β,14α,21-tri-hydroxy-diosgenin (42), and 11β,14α-di-hydroxyldiosgenin (43) were purchase from Sichuan weikeqi biotechnology company (Sichuan province, China). Pooled human liver microsomes (HLMs, 20 mg/mL) and pooled human primary hepatocytes were purchased from Rild Research Institute for LiverDiseases (Shanghai, China).

Pseudoprotodioscin inhibits SREBPs and microRNA 33a/b levels and reduces the gene expression regarding the synthesis of cholesterol and triglycerides
Source:SCI:FITOTERAPIA Author:Yanan Gai Notes:影響因子:2.431
Reference description

for the Control of Pharmaceutical and Biological Products (Beijing, China) (Fig. 1a). Dioscin (DC), pseudoprotodioscin (PPD) and methylprotodioscin (MP) were bought from Sichuan Weikeqi Biological Technology Co. Ltd. (Sichuan, China) (Fig. 1a).

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